Furthermore, we discuss how AdRCs facilitate the interplay between viral and cellular machineries and hijack cellular functions to promote viralgenomereplication and expression.
2
Double-stranded RNA intermediates generated during viralgenomereplication are recognised by host innate immune sensors in the cytoplasm, activating the strongly antiviral interferon gene programme.
3
Viralgenomereplication was unaffected, and inhibition could be elicited late in infection and persisted upon drug removal.
Ús de virus replication en anglès
1
HIV-specific proliferation returned when therapy was resumed and virusreplication was controlled.
2
It was found that mutations preventing nsP1 palmitoylation also attenuated virusreplication.
3
Finally, we revealed that the inhibition of miR29c marvelously accelerated virusreplication.